Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373369 | 0.83 | L3MBTL1 (0.34) | APOBEC3AAPOBEC3G | |
| SCHEMBL9623555 | 0.68 | LMNA (0.33) | APOBEC3AAPOBEC3G | |
| SCHEMBL7412862 | 0.67 | KDM4E (0.42) | — | |
| SCHEMBL7358639 | 0.66 | — | — | |
| SCHEMBL7375008 | 0.66 | PDE4A (0.35) | APOBEC3AAPOBEC3G | |
| SCHEMBL12827526 | 0.66 | NPC1 (0.30) | — | |
| SCHEMBL19797901 | 0.65 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GDPP4 | |
| SCHEMBL7382377 | 0.64 | SIRT3 (0.33) | — | |
| SCHEMBL7377175 | 0.64 | HTT (0.46) | — | |
| SCHEMBL7379327 | 0.62 | MPO (0.34) | APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165500-A1 | AMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES,TNF-ALPHA,AND AGGRECANASE | Du Pont Pharmaceuticals Company (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059874-A1 | NOVEL AMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES, TNF-α, AND AGGRECANASE | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |