Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.54 |
| ▸ | PGR | P06401 | 5/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR1E | P28566 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739201 | 0.88 | HTR2A (0.66) | NR3C1ADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL14615471 | 0.87 | NR3C1 (0.55) | NR3C1NR3C2PGRADRB1HTR1A | |
| SCHEMBL737936 | 0.81 | GHSR (0.56) | NR3C1NR3C2PGRADRB1HTR1A | |
| SCHEMBL739054 | 0.80 | KDM4E (0.58) | ADRB1HTR1AADRA2ASLC6A2HTR1D | |
| SCHEMBL22633473 | 0.77 | MMP9 (0.71) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL22633475 | 0.77 | MMP9 (0.71) | KDM4EAPAF1POLBMAPTRECQL | |
| SCHEMBL4206927 | 0.76 | HTR2A (0.80) | NR3C1NR3C2PGRADRB1HTR1A | |
| SCHEMBL739053 | 0.75 | HTR2A (0.69) | ADRB1HTR1AADRA2ASLC6A2HTR1D | |
| SCHEMBL3127763 | 0.75 | NR3C1 (0.77) | NR3C1NR3C2PGR | |
| SCHEMBL12967597 | 0.75 | KCNA5 (0.67) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138218-B2 | Growth hormone secretagogues | IPSEN PHARMA S.A.S. (FR) | 2012-03-20 | — | — | US | disclosed |
| US-20090131478-A1 | Growth Hormone Secretagogues | IPSEN PHARMA S.A.S. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131478-A1 | Growth Hormone Secretagogues | GHSR, GHRHR, GHITM | NR3C1 192/4885NR3C2 127/4885PGR 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.