SCHEMBL29360810

SCHEMBL29360810

NC(=O)c1cccc2[nH]ncc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 2/20 0.56
BTK Q06187 2/20 0.56
PLK4 O00444 1/20 0.56
CHEK1 O14757 1/20 0.56
AURKA O14965 1/20 0.56
DAPK3 O43293 1/20 0.56
MAP4K4 O95819 1/20 0.56
RET P07949 1/20 0.56
FGFR1 P11362 1/20 0.56
PDGFRA P16234 1/20 0.56
LTK P29376 1/20 0.56
KDR P35968 1/20 0.56
MAP2K2 P36507 1/20 0.56
FLT3 P36888 1/20 0.56
CSNK1A1 P48729 1/20 0.56
PRKX P51817 1/20 0.56
CDK5 Q00535 1/20 0.56
MAP2K1 Q02750 1/20 0.56
MST1R Q04912 1/20 0.56
PTK2 Q05397 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1134888 1.00 CSF1R (0.56) CSF1RBTKPLK4CHEK1AURKA
SCHEMBL31409300 0.85 METAP2 (0.55) CSF1RBTKPLK4CHEK1AURKA
SCHEMBL30285533 0.84 NOS1 (0.52) NOS1AXLIDO1METAP2KIT
SCHEMBL260364 0.84 NOS1 (0.52) NOS1AXLIDO1METAP2KIT
Hydrochloric Acid SCHEMBL1056437 0.82 NOS1 (0.50) NOS1AXLIDO1METAP2KIT
SCHEMBL7379757 0.82 NOS1 (0.50) NOS1AXLIDO1METAP2KIT
SCHEMBL1743327 0.82 CTNNB1 (0.49) CSF1RBTKPLK4CHEK1AURKA
SCHEMBL459667 0.81 METTL3 (0.52) KITNPC1LMNACYP1A2CYP3A4
SCHEMBL29702928 0.81 NOS1 (0.53) NOS1AXLIDO1METAP2KIT
SCHEMBL6531813 0.80 NOS1 (0.53) CSF1RBTKPLK4CHEK1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4639437-A1 SYSTEMS AND METHODS FOR PEST PRESSURE HEAT MAPS THAT CONVEY INFORMATION RELATING TO GENETIC MARKERS OF RESISTANCE TO PEST CONTROL PRODUCTS FMC Corporation (US) 2025-10-29 EP disclosed
US-12358915-B2 METTL3 inhibitory compounds STORM Therapeutics Ltd. (GB) 2025-07-15 US disclosed
US-12274697-B2 Compositions and methods for treating EZH2-mediated cancer ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2025-04-15 US disclosed
EP-4496475-A2 PROCESSES FOR CRYSTALLIZATION OF AMORPHOUS PESTICIDES AND FORMULATIONS THEREOF FMC Corporation (US) 2025-01-29 EP disclosed
WO-2024137332-A1 SYSTEMS AND METHODS FOR PEST PRESSURE HEAT MAPS THAT CONVEY INFORMATION RELATING TO GENETIC MARKERS OF RESISTANCE TO PEST CONTROL PRODUCTS FMC CORPORATION (US) 2024-06-27 WO disclosed
US-20230383292-A1 TARGETING XIST AND RNA METHYLATION FOR X REACTIVATION THERAPY THE GENERAL HOSPITAL CORPORATION 2023-11-30 US disclosed
WO-2023183353-A2 PROCESSES FOR CRYSTALLIZATION OF AMORPHOUS PESTICIDES AND FORMULATIONS THEREOF FMC CORPORATION (US) 2023-09-28 WO disclosed
US-20230114294-A1 COMPOSITIONS AND METHODS FOR TREATING EZH2-MEDIATED CANCER ICAHN SCHOOL MED MOUNT SINAI (US) 2023-04-13 US disclosed
US-20230085408-A1 METTL3 INHIBITORY COMPOUNDS STORM THERAPEUTICS LIMITED (GB) 2023-03-16 US disclosed
CN-113999211-B Indazole skeleton derivative containing 1,2,3-triazole with specific activity of resisting prostate cancer 郑州大学 2022-11-29 CN disclosed
US-11510920-B2 Compositions and methods for treating EZH2-mediated cancer ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2022-11-29 US disclosed
CN-110885328-B Sulfonamide compounds as sodium channel blockers and uses thereof 成都康弘药业集团股份有限公司 2022-08-12 CN disclosed
WO-2022017836-A1 FUNGICIDAL COMPOSITIONS COMPRISING (R)-2-[4-(4-CHLOROPHENOXY)-2-(TRIFLUOROMETHYL)PHENYL]-1- (1,2,4-TRIAZOL-1-YL)PROPAN-2-OL BASF Agro B.V. (NL) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358915-B2 METTL3 inhibitory compounds METTL3, METTL16, DIMT1 CSF1R 2614/4885BTK 2457/4885PLK4 3124/4885
US-12274697-B2 Compositions and methods for treating EZH2-mediated cancer EZH2, EZH1, EED CSF1R 4135/4885BTK 2009/4885PLK4 1797/4885
US-20230383292-A1 TARGETING XIST AND RNA METHYLATION FOR X REACTIVATION THERAPY METTL16, NSUN2, METTL3 CSF1R 3258/4885BTK 1014/4885PLK4 3677/4885
US-11510920-B2 Compositions and methods for treating EZH2-mediated cancer EZH2, EZH1, EED CSF1R 4135/4885BTK 2009/4885PLK4 1797/4885
US-20230114294-A1 COMPOSITIONS AND METHODS FOR TREATING EZH2-MEDIATED CANCER EZH2, EZH1, EED CSF1R 4135/4885BTK 2009/4885PLK4 1797/4885
US-20230085408-A1 METTL3 INHIBITORY COMPOUNDS METTL3, METTL16, DIMT1 CSF1R 2614/4885BTK 2457/4885PLK4 3124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.