Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP7 | P09237 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP10 | P09238 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580313 | 0.73 | CTSK (0.56) | MMP7MMP9MMP10HRH3AIMP2 | |
| SCHEMBL6580632 | 0.69 | CACNA1B (0.50) | MMP7MMP9MMP10AIMP2MEN1 | |
| SCHEMBL29885303 | 0.66 | MAPT (0.59) | MMP7MMP9MMP10AIMP2MEN1 | |
| SCHEMBL31086808 | 0.65 | MMP7 (0.56) | MMP7MMP9MMP10AIMP2MEN1 | |
| SCHEMBL5850011 | 0.62 | GAA (0.48) | MMP7MMP9MEN1KMT2AL3MBTL1 | |
| SCHEMBL6096482 | 0.61 | HTR7 (0.61) | KCNH2 | |
| SCHEMBL5180596 | 0.61 | MMP7 (0.76) | MMP7MMP9MMP10L3MBTL1MMP1 | |
| SCHEMBL31086829 | 0.61 | ALDH1A1 (0.68) | MMP7MMP9AIMP2MEN1KMT2A | |
| SCHEMBL7062934 | 0.61 | ALDH1A1 (0.68) | MMP7MMP9AIMP2MEN1KMT2A | |
| SCHEMBL15252003 | 0.61 | ALDH1A1 (0.68) | MMP7MMP9AIMP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-A4 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 1999-10-13 | — | — | EP | claimed |
| EP-0936912-A1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-25 | — | — | EP | claimed |
| WO-1998005336-A1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-12 | — | — | WO | claimed |