Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.46 |
| ▸ | ACE | P12821 | 7/20 | 0.46 |
| ▸ | CPA1 | P15085 | 7/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647590 | 0.84 | MME (0.48) | MMEACECPA1ACE2 | |
| SCHEMBL11074641 | 0.84 | MME (0.48) | MMEACECPA1ACE2 | |
| SCHEMBL7377272 | 0.84 | MME (0.56) | MMEACECPA1ACE2 | |
| SCHEMBL7374671 | 0.84 | REN (0.39) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7381805 | 0.84 | ALDH1A1 (0.41) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL10648066 | 0.84 | ALDH1A1 (0.41) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL10647242 | 0.84 | ALDH1A1 (0.41) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7381161 | 0.83 | TACR1 (0.48) | MMEACEALDH1A1POLB | |
| SCHEMBL7383447 | 0.83 | ACE (0.46) | MMEACE | |
| SCHEMBL10449998 | 0.82 | CTSL (0.40) | ACEALDH1A1THRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610816-A | ANALGESICS | SCHERING CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |