Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.56 |
| ▸ | ACE | P12821 | 7/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.51 |
| ▸ | CPA1 | P15085 | 6/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647590 | 0.88 | MME (0.48) | MMEACEACE2CPA1 | |
| SCHEMBL11074641 | 0.88 | MME (0.48) | MMEACEACE2CPA1 | |
| SCHEMBL11074282 | 0.87 | CTSS (0.42) | MMEACEACE2CPA1 | |
| SCHEMBL7381161 | 0.86 | TACR1 (0.48) | MMEACE | |
| SCHEMBL11072416 | 0.86 | MME (0.42) | MMEACEACE2CPA1 | |
| SCHEMBL7373720 | 0.85 | MMEL1 (0.51) | MMEACE | |
| SCHEMBL10713161 | 0.85 | L3MBTL1 (0.43) | MMEACEACE2CPA1 | |
| SCHEMBL7374304 | 0.85 | MMEL1 (0.51) | MMEACE | |
| SCHEMBL7375938 | 0.84 | MME (0.42) | MMEACEACE2CPA1 | |
| SCHEMBL7377914 | 0.84 | MME (0.42) | MMEACEACE2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906615-A | Substituted dipeptides as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0103077-B1 | SUBSTITUTED DIPEPTIDES, METHODS FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, METHOD FOR MAKING SUCH PHARMACEUTICAL COMPOSITIONS | SCHERING CORPORATION (US) | 1988-05-18 | — | — | EP | disclosed |
| US-4721726-A | ANALGESICS | SCHERING CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4610816-A | ANALGESICS | SCHERING CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0103077-A2 | Substituted dipeptides, methods for their production, pharmaceutical compositions containing them, method for making such pharmaceutical compositions | SCHERING CORPORATION (US) | 1984-03-21 | — | — | EP | disclosed |