Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14656642 | 0.79 | OPRM1 (0.36) | OPRM1GPR119 | |
| SCHEMBL14343273 | 0.79 | OPRM1 (0.36) | OPRM1GPR119 | |
| SCHEMBL7366551 | 0.78 | OPRM1 (0.32) | OPRM1 | |
| SCHEMBL642483 | 0.76 | AKR1C1 (0.37) | — | |
| SCHEMBL7364415 | 0.76 | AKR1C1 (0.37) | — | |
| SCHEMBL4302396 | 0.75 | HPGD (0.30) | — | |
| Bromide SCHEMBL7340605 | 0.75 | AKR1C1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL1357987 | 0.75 | AKR1C1 (0.36) | — | |
| SCHEMBL14343367 | 0.75 | P4HB (0.32) | ELANEOPRM1USP30GPR119 | |
| SCHEMBL7379886 | 0.74 | HRH3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053902-B1 | PHOSPHINYLALKANOYL SUBSTITUTED PROLINES | E.R. Squibb & Sons, Inc. (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4384123-A | Phosphinylalkanoyl substituted prolines | E. R. SQUIBB & SONS, INC. (US) | 1983-05-17 | — | — | US | disclosed |
| US-4337201-A | Phosphinylalkanoyl substituted prolines | E. R. SQUIBB & SONS, INC. (US) | 1982-06-29 | — | — | US | disclosed |
| EP-0053902-A1 | Phosphinylalkanoyl substituted prolines | E.R. Squibb & Sons, Inc. (US) | 1982-06-16 | — | — | EP | disclosed |