Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.40 |
| ▸ | ITGAV | P06756 | 5/20 | 0.40 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380345 | 0.86 | KCNK3 (0.50) | KCNK3KCNK9ITGB3ITGA2BITGAV | |
| SCHEMBL7380190 | 0.85 | KCNK3 (0.46) | KCNK3KCNK9ITGB3ITGA2BITGAV | |
| SCHEMBL7379952 | 0.82 | ITGB3 (0.48) | KCNK3KCNK9ITGB3ITGA2BITGAV | |
| SCHEMBL7380550 | 0.80 | ITGB3 (0.43) | KCNK3KCNK9ITGB3ITGA2BITGAV | |
| SCHEMBL7380126 | 0.79 | ITGB3 (0.53) | KCNK3KCNK9ITGB3ITGA2BITGAV | |
| SCHEMBL7378628 | 0.79 | SMN1; SMN2 (0.55) | KCNK3KCNK9ITGB3ITGA2BITGAV | |
| SCHEMBL7373860 | 0.78 | PTGER1 (0.44) | KCNK3KCNK9ITGB3ITGA2BITGAV | |
| SCHEMBL8369251 | 0.77 | CASP3 (0.52) | KCNK3KCNK9SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7377645 | 0.77 | BCHE (0.49) | BCHESMN1; SMN2PPARGLMNAMAPT | |
| SCHEMBL7378811 | 0.77 | PTGER4 (0.48) | KCNK3KCNK9ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |