Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380504 | 0.83 | ACHE (0.50) | ACHEFAAHTSHRRECQL | |
| SCHEMBL19239794 | 0.71 | ACHE (0.46) | ACHETSHR | |
| SCHEMBL22848588 | 0.71 | TSHR (0.57) | ACHEFAAHTSHRRECQL | |
| SCHEMBL22527258 | 0.71 | TSHR (0.57) | ACHEFAAHTSHRRECQL | |
| SCHEMBL11840937 | 0.71 | TSHR (0.61) | ACHEFAAHTSHRRECQL | |
| SCHEMBL22525311 | 0.71 | TSHR (0.57) | ACHEFAAHTSHRRECQL | |
| SCHEMBL30163718 | 0.71 | ACHE (0.60) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12972503 | 0.71 | ACHE (0.51) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4756402 | 0.70 | ACHE (0.69) | ACHE | |
| SCHEMBL19168532 | 0.70 | TSHR (0.56) | ACHEFAAHTSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002070521-A1 | NOVEL METALLOPROTEINASE INHIBITOR DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2002-09-12 | — | — | WO | disclosed |