Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952639 | 1.00 | MAPT (0.55) | MAPTMAPK1NPSR1AHRHTR6 | |
| SCHEMBL6953567 | 0.85 | AHR (0.55) | MAPTMAPK1NPSR1AHRHTR6 | |
| SCHEMBL12808068 | 0.83 | RAB9A (0.60) | MAPTMAPK1NPSR1AHRHTR6 | |
| SCHEMBL31405650 | 0.81 | ALDH1A1 (0.59) | MAPTMAPK1NPSR1AHRHTR6 | |
| SCHEMBL13485647 | 0.80 | AHR (0.59) | MAPTAHRRAB9ACYP1A2CYP3A4 | |
| SCHEMBL10082865 | 0.80 | RAB9A (0.57) | MAPTAHRRAB9ACYP1A2CYP3A4 | |
| SCHEMBL24405131 | 0.79 | HTR6 (0.66) | MAPTAHRHTR6RAB9AL3MBTL1 | |
| SCHEMBL6330362 | 0.79 | OXER1 (0.56) | MAPTAHRRAB9ACYP1A2CYP3A4 | |
| SCHEMBL3886866 | 0.79 | HTR6 (0.63) | MAPTMAPK1NPSR1HTR6CYP1A2 | |
| SCHEMBL7847012 | 0.79 | KDM4E (0.63) | MAPTMAPK1NPSR1AHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255830-A | S1PR2 modulators and uses thereof | 北京昌平实验室 | 2024-06-28 | — | — | CN | disclosed |
| EP-0420086-B1 | Pyrimidoindole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5256780-A | Serotonin antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| US-5180728-A | Antagonists of 5-hydroxytryptamine | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0420086-A2 | Pyrimidoindole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |