Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380370 | 0.90 | DRD2 (0.55) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL7381604 | 0.88 | DRD2 (0.44) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL7382363 | 0.88 | DRD2 (0.48) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL3314494 | 0.81 | DRD2 (0.53) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL21055572 | 0.81 | DRD2 (0.53) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL21054909 | 0.81 | DRD2 (0.53) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL10726714 | 0.78 | DRD2 (0.51) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL7372752 | 0.78 | LMNA (0.47) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL10559503 | 0.78 | DRD2 (0.53) | DRD2LMNAADRA2AALOX15TSHR | |
| SCHEMBL10564984 | 0.78 | DRD2 (0.52) | DRD2LMNAADRA2AALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401822-A | ANISEROTONINE AGENTS; APOMORPHINE ANTAGONIST | SOCIETE DE'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE FRANCE (FR) | 1983-08-30 | — | — | US | disclosed |
| US-4294828-A | ANTIEMETIC AND ANTISEROTONIN | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE-FRANCE (FR) | 1981-10-13 | — | — | US | disclosed |