Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980169 | 0.84 | MEN1 (0.32) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL16699764 | 0.81 | THRB (0.34) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL22229966 | 0.78 | GABBR2 (0.33) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL203296 | 0.78 | GABRP (0.37) | ALDH1A1MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL1248340 | 0.78 | GABRP (0.37) | ALDH1A1MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL13731404 | 0.75 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL14481587 | 0.75 | ALDH1A1 (0.34) | TRPA1ALDH1A1ALOX15 | |
| SCHEMBL1952760 | 0.75 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL1979048 | 0.75 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL16862540 | 0.74 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196410-A1 | RESPIRATORY SYNCYTIAL VIRUS REPLICATION INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001000615-A1 | RESPIRATORY SYNCYTIAL VIRUS REPLICATION INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-01-04 | — | — | WO | disclosed |