Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381813 | 1.00 | GAA (0.58) | GAAPOLBALDH1A1NPSR1LMNA | |
| SCHEMBL395086 | 0.74 | HSD11B1 (0.64) | HSD11B1NR1H2NR1H3 | |
| SCHEMBL3455531 | 0.73 | GAA (0.60) | GAAPOLBALDH1A1NPSR1LMNA | |
| SCHEMBL12204828 | 0.72 | POLB (0.74) | GAAPOLBALDH1A1NPSR1LMNA | |
| SCHEMBL766158 | 0.71 | ALDH1A1 (0.60) | GAAPOLBALDH1A1NPSR1LMNA | |
| SCHEMBL1577378 | 0.69 | HSD11B1 (0.57) | HSD11B1NR1H2NR1H3 | |
| SCHEMBL1577665 | 0.69 | HSD11B1 (0.54) | HSD11B1NR1H2NR1H3 | |
| SCHEMBL30107924 | 0.69 | HSD11B1 (0.54) | HSD11B1NR1H2NR1H3 | |
| SCHEMBL8472020 | 0.67 | OXTR (0.57) | HSD11B1 | |
| SCHEMBL3457632 | 0.67 | LMNA (0.61) | GAAPOLBALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450761-A1 | Spirocyclic oxytocin antagonists | MERCK & CO. INC. (US) | 1991-10-09 | — | — | EP | claimed |