Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.36 |
| ▸ | PARG | Q86W56 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | GSR | P00390 | 3/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7471306 | 0.85 | F2 (0.41) | F2PRSS1MEN1KMT2ARAPGEF3 | |
| SCHEMBL7381947 | 0.81 | MEN1 (0.35) | F2PARGMEN1KMT2ARAPGEF3 | |
| SCHEMBL2364436 | 0.79 | F10 (0.38) | F2PRSS1PARGMEN1KMT2A | |
| SCHEMBL7385658 | 0.77 | PARG (0.36) | F2PRSS1PARGMEN1KMT2A | |
| SCHEMBL7384883 | 0.74 | F10 (0.40) | F2PARGMEN1KMT2ARAPGEF3 | |
| SCHEMBL7544010 | 0.73 | F10 (0.63) | F2PRSS1F10KLK6 | |
| SCHEMBL7382892 | 0.72 | NCF1 (0.43) | F2PRSS1MEN1KMT2ARAPGEF3 | |
| SCHEMBL7382854 | 0.72 | GSR (0.39) | F2PRSS1MEN1KMT2ARAPGEF3 | |
| SCHEMBL7374683 | 0.70 | F10 (0.37) | F2PARGRAPGEF3F10 | |
| Trifluoroacetic Acid SCHEMBL7385566 | 0.70 | RAPGEF3 (0.35) | F2PRSS1MEN1KMT2ARAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944386-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0944386-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025611-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-18 | — | — | WO | disclosed |