Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.38 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 4/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382013 | 0.79 | F2 (0.36) | F10KLK6RAPGEF3POLBNPSR1 | |
| SCHEMBL7384883 | 0.78 | F10 (0.40) | F10RAPGEF3POLBNPSR1MEN1 | |
| SCHEMBL7382892 | 0.75 | NCF1 (0.43) | F10RAPGEF3MEN1KMT2AF2 | |
| SCHEMBL7374683 | 0.74 | F10 (0.37) | F10RAPGEF3PARGPLAUF2 | |
| SCHEMBL7385658 | 0.74 | PARG (0.36) | F10RAPGEF3POLBNPSR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL7471306 | 0.74 | F2 (0.41) | F10KLK6RAPGEF3MEN1KMT2A | |
| SCHEMBL7381947 | 0.73 | MEN1 (0.35) | F10RAPGEF3POLBNPSR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL7374889 | 0.70 | NOS1 (0.46) | F10RAPGEF3F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7375646 | 0.70 | RAPGEF3 (0.35) | F10RAPGEF3MEN1KMT2APLAU | |
| SCHEMBL7375549 | 0.70 | F10 (0.37) | F10RAPGEF3KMT2APARGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-B1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2011-08-17 | — | — | EP | disclosed |