⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012166 | 0.67 | — | — | |
| SCHEMBL449021 | 0.54 | — | — | |
| SCHEMBL690409 | 0.45 | — | — | |
| SCHEMBL423198 | 0.45 | — | — | |
| SCHEMBL5162 | 0.43 | — | — | |
| SCHEMBL24617 | 0.35 | — | — | |
| Calcium Bromide SCHEMBL30888723 | 0.34 | — | — | |
| Perbromobenzene SCHEMBL27124 | 0.34 | ALDH1A1 (0.50) | — | |
| SCHEMBL284725 | 0.29 | — | — | |
| Methane SCHEMBL23044967 | 0.25 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092788-B | Substituted [1,2,4] triazolo [1,5-a ] pyrimidin-7-yl compounds as PDE2 inhibitors | 达特神经科学(开曼)有限公司 | 2022-02-25 | — | — | CN | claimed |
| EP-3597649-B1 | COMPOSITIONS CONTAINING SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS | DART NEUROSCIENCE CAYMAN LTD (KY) | 2021-10-13 | — | — | EP | claimed |
| EP-3134413-B1 | SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS | DART NEUROSCIENCE CAYMAN LTD (KY) | 2019-09-11 | — | — | EP | claimed |
| US-9932345-B2 | Substituted [1,2,4]triazolo[1,5-A]pyrimidin-7-yl compounds as PDE2 inhibitors | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2018-04-03 | — | — | US | claimed |
| US-20170057967-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS | DART NEUROSCIENCE LLC | 2017-03-02 | — | — | US | claimed |
| EP-3134413-A1 | SUBSTITUTED [1,2,4]TRIAZOLO [1,5-A]PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS | Dart Neuroscience (Cayman) Ltd (KY) | 2017-03-01 | — | — | EP | claimed |
| EP-2049488-B1 | N'-CYANO-N-ALKYL HALIDE IMIDE AMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2015-12-09 | — | — | EP | claimed |
| WO-2015164508-A1 | SUBSTITUTED [1,2,4] TRIAZOLO [1,5-A] PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS | DART NEUROSCIENCE, LLC (US) | 2015-10-29 | — | — | WO | claimed |
| US-20140113824-A1 | BICYCLIC (THIO)CARBONYLAMIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-24 | — | — | US | claimed |
| EP-2021344-B1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2013-05-08 | — | — | EP | claimed |
| CN-1245854-A | Processed timber | SUMITOMO CHEMICAL CO (JP) | 2000-03-01 | — | — | CN | claimed |
| EP-0976328-A2 | Ectoparasite controlling agent for animals | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | claimed |
| EP-0966961-A1 | Method for controlling ectoparasites | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-12-29 | — | — | EP | claimed |
| EP-0366085-B1 | Tetrahydropyrimidines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-04-17 | — | — | EP | claimed |
| EP-0496106-B1 | Stable agrochemical compositions | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-12-20 | — | — | EP | claimed |
| EP-0496106-A1 | Stable agrochemical compositions | Takeda Chemical Industries, Ltd. (JP) | 1992-07-29 | — | — | EP | claimed |
| CN-1063014-A | Stable composition pesticide | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-07-29 | — | — | CN | claimed |
| US-4427688-A | N-Substituted 2-methylnaphthylamides, their preparation, and their use for controlling fungi | BASF AKTIENGESELLSCHAFT (DE) | 1984-01-24 | — | — | US | claimed |
| EP-0073973-A1 | Thiazolyl and isothiazolyl-carboxylic-acid anilides, process for their preparation and their utilization as fungicides | BASF Aktiengesellschaft (DE) | 1983-03-16 | — | — | EP | claimed |
| EP-0065723-A1 | N-substituted 2-methylnaphthyl amides, their preparation and their use as fungicides | BASF Aktiengesellschaft (DE) | 1982-12-01 | — | — | EP | claimed |