Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383227 | 0.83 | TUBB1 (0.53) | TUBB1ERN1MAOBBCHEKDM4E | |
| SCHEMBL9302788 | 0.79 | SRD5A2 (0.54) | MAOBMAPTHTT | |
| SCHEMBL6069413 | 0.78 | MAOB (0.49) | TUBB1ERN1MAOBBCHEKDM4E | |
| SCHEMBL20815159 | 0.78 | TUBB1 (0.58) | TUBB1ERN1MAOBBCHEKDM4E | |
| SCHEMBL435043 | 0.78 | ALDH1A1 (0.61) | TUBB1ERN1MAOBAPPHDAC8 | |
| SCHEMBL6035502 | 0.78 | TUBB1 (0.72) | TUBB1ERN1MAOBMAPT | |
| SCHEMBL10797158 | 0.76 | MAOB (0.72) | MAOBPARP15KDM4EMAPT | |
| SCHEMBL21755487 | 0.76 | PARP15 (0.56) | MAOBPARP15APPKDM4E | |
| SCHEMBL9304203 | 0.76 | MAOB (0.48) | ERN1MAOBMAPTHTTPDE4A | |
| SCHEMBL1448026 | 0.75 | MAOB (0.61) | MAOBPARP15KDM4ECTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998038168-A1 | ISOQUINOLINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1998-09-03 | — | — | WO | disclosed |