Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383233 | 0.78 | TUBB1 (0.55) | MAOBTUBB1ERN1BCHEKDM4E | |
| SCHEMBL6070482 | 0.77 | TUBB1 (0.42) | MAOBTUBB1ERN1MGAMGAA | |
| SCHEMBL7282913 | 0.77 | MAOB (0.68) | MAOBMAOAMAPT | |
| SCHEMBL5805630 | 0.76 | TUBB1 (0.45) | MAOBTUBB1ERN1BCHEMGAM | |
| SCHEMBL2744173 | 0.75 | KDM4E (0.52) | ERN1GAAKDM4EMAPT | |
| SCHEMBL10797158 | 0.74 | MAOB (0.72) | MAOBGAAMAOAKDM4EMAPT | |
| SCHEMBL18533013 | 0.73 | BCHE (0.48) | MAOBTUBB1ERN1BCHEMGAM | |
| SCHEMBL435043 | 0.73 | ALDH1A1 (0.61) | MAOBTUBB1ERN1MAOAKDM4E | |
| SCHEMBL6035502 | 0.73 | TUBB1 (0.72) | MAOBTUBB1ERN1MEN1KMT2A | |
| SCHEMBL3365964 | 0.72 | MAPT (0.58) | MAOBMEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067416-A1 | CHEMICAL PROCESSES AND INTERMEDIATES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |