Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381037 | 1.00 | CTSL (0.49) | CTSLFKBP1AKMT2AMEN1SYK | |
| SCHEMBL4676316 | 0.84 | CTSK (0.53) | CTSLKMT2ASYKL3MBTL1PREP | |
| SCHEMBL4676319 | 0.84 | CTSK (0.53) | CTSLKMT2ASYKL3MBTL1PREP | |
| SCHEMBL4678408 | 0.84 | CTSK (0.53) | CTSLKMT2ASYKL3MBTL1PREP | |
| SCHEMBL25292925 | 0.81 | MEN1 (0.47) | CTSLFKBP1AKMT2AMEN1STS | |
| SCHEMBL606732 | 0.79 | CTSL (0.52) | CTSLFKBP1AKMT2AMEN1SYK | |
| SCHEMBL19586208 | 0.77 | FKBP1A (0.47) | CTSLFKBP1AKMT2AMEN1STS | |
| SCHEMBL27692260 | 0.76 | NPC1 (0.46) | CTSLFKBP1AKMT2AMEN1L3MBTL1 | |
| SCHEMBL30986395 | 0.76 | MEN1 (0.54) | FKBP1AKMT2AMEN1HPGD | |
| SCHEMBL27935766 | 0.76 | KMT2A (0.46) | CTSLKMT2AMEN1L3MBTL1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975612-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2001-06-13 | — | — | EP | claimed |
| EP-0975612-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-02 | — | — | EP | claimed |
| WO-1998046582-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-22 | — | — | WO | claimed |
| EP-0975612-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-0975612-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046582-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-22 | — | — | WO | disclosed |