SCHEMBL738428

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23784620	0.94	NOTUM (0.37)	NOTUMPDE3BPDE3APDK2CA1
	SCHEMBL1796306	0.92	NOTUM (0.36)	NOTUMPDE3BPDE3APDK2CA1
	SCHEMBL2529138	0.90	PDK2 (0.45)	NOTUMPDK2CA1CA2KDM4E
	SCHEMBL3108151	0.89	PDK2 (0.36)	NOTUMPDK2CA1CA2KDM4E
	SCHEMBL23778641	0.89	KDM4E (0.39)	NOTUMPDK2CA1CA2KDM4E
	SCHEMBL362563	0.89	KDM4E (0.39)	NOTUMPDK2CA1CA2KDM4E
	SCHEMBL737462	0.89	PDE3B (0.36)	NOTUMPDE3BPDE3ACA1CA2
	SCHEMBL738671	0.89	PDK2 (0.36)	NOTUMPDK2CA1CA2KDM4E
	SCHEMBL11960920	0.89	ABL1 (0.44)	PDK2CA1CA2KDM4EMAPT
	SCHEMBL738679	0.89	CA1 (0.37)	NOTUMPDK2CA1CA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.