SCHEMBL738671

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2529138	0.90	PDK2 (0.45)	PDK2CA1CA2KDM4EF2
	SCHEMBL23778641	0.89	KDM4E (0.39)	PDK2CA1CA2KDM4EF2
	SCHEMBL362563	0.89	KDM4E (0.39)	PDK2CA1CA2KDM4EF2
	SCHEMBL3108151	0.89	PDK2 (0.36)	PDK2CA1CA2KDM4EF2
	SCHEMBL738679	0.89	CA1 (0.37)	PDK2CA1CA2KDM4EF2
	SCHEMBL738428	0.89	NOTUM (0.39)	PDK2CA1CA2KDM4EF2
	SCHEMBL11960920	0.89	ABL1 (0.44)	PDK2CA1CA2KDM4EF2
	SCHEMBL739992	0.88	CA1 (0.33)	PDK2CA1CA2LTB4RLTB4R2
	SCHEMBL1799389	0.88	NPC1 (0.36)	PDK2CA1CA2KDM4EF2
	SCHEMBL12846406	0.87	CA1 (0.32)	CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.