Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP7 | P09237 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 11/20 | 0.39 |
| ▸ | CTSL | P07711 | 6/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384628 | 0.91 | MMP1 (0.40) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL7762274 | 0.82 | CTSK (0.42) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL6414560 | 0.81 | MMP3 (0.46) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8388142 | 0.78 | PSMB5 (0.46) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL7376979 | 0.76 | CTSK (0.44) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL7377048 | 0.76 | CTSK (0.41) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL7481783 | 0.75 | MMP1 (0.48) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL7380606 | 0.74 | CTSK (0.40) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8385691 | 0.74 | PSMB5 (0.46) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8387026 | 0.73 | MMP1 (0.59) | MMP1MMP2MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946166-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998026773-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |