SCHEMBL738463

SCHEMBL738463

C=CC(=O)Oc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.62
THRB P10828 2/20 0.49
ALDH1A1 P00352 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
RXRA P19793 3/20 0.47
BCL2L1 Q07817 1/20 0.47
BAD Q92934 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
RARB P10826 5/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
RXRB P28702 2/20 0.43
SRD5A2 P31213 1/20 0.43
RARA P10276 1/20 0.43
RARG P13631 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1894950 0.94 HSD17B10 (0.53) HSD17B10THRBALDH1A1L3MBTL1CA1
SCHEMBL15695636 0.88 THRB (0.58) HSD17B10THRBALDH1A1LMNAGAA
SCHEMBL802752 0.88 THRB (0.58) HSD17B10THRBALDH1A1LMNAGAA
Hydroquinone SCHEMBL28396105 0.87 CA2 (0.57) HSD17B10THRBALDH1A1L3MBTL1CA1
SCHEMBL534168 0.87 PARP10 (0.50) HSD17B10THRBALDH1A1L3MBTL1CA1
SCHEMBL22566606 0.85 THRB (0.49) HSD17B10THRBALDH1A1L3MBTL1LMNA
SCHEMBL21470125 0.85 THRB (0.49) HSD17B10THRBALDH1A1L3MBTL1LMNA
SCHEMBL22566480 0.85 THRB (0.49) HSD17B10THRBALDH1A1L3MBTL1LMNA
SCHEMBL15695635 0.85 THRB (0.49) HSD17B10THRBALDH1A1L3MBTL1LMNA
SCHEMBL8927324 0.85 THRB (0.51) HSD17B10THRBLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115404699-B Preparation method of multifunctional textile after-finishing auxiliary, product and application thereof 盐城工学院 2023-07-25 CN claimed
CN-115404699-A Preparation method of multifunctional textile after-finishing auxiliary, product and application thereof 盐城工学院 2022-11-29 CN claimed
CN-115916853-B Polymer, and photo-alignment film and retardation film using the same 大阪有机化学工业株式会社 2024-07-09 CN disclosed
CN-115404699-B Preparation method of multifunctional textile after-finishing auxiliary, product and application thereof 盐城工学院 2023-07-25 CN disclosed
CN-115916853-A Novel polymer, and photo-alignment film and retardation film using same 大阪有机化学工业株式会社 2023-04-04 CN disclosed
CN-115404699-A Preparation method of multifunctional textile after-finishing auxiliary, product and application thereof 盐城工学院 2022-11-29 CN disclosed
US-8471055-B2 Photo-crosslinkable liquid crystal monomers with optical activity CHUNGHWA PICTURE TUBES, LTD. (TW) 2013-06-25 US disclosed
US-8436103-B2 Star polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2013-05-07 US disclosed
US-8436103-B2 Star polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2013-05-07 US disclosed
US-20120289731-A1 PHOTO-CROSSLINKABLE LIQUID CRYSTAL MONOMERS WITH OPTICAL ACTIVITY NATIONAL CHIAO TUNG UNIVERSITY (TW) 2012-11-15 US disclosed
EP-2341510-B1 Blockcopolymer solid electrolyte, ion-conductive membrane and process for producing the blockcopolymer NIPPON SODA CO (JP) 2012-10-31 EP disclosed
US-7645830-B2 Polymer, crosslinked polymer, composition for solid polymer electrolyte, solid polymer electrolyte, and adhesive composition NIPPON SODA CO., LTD. (JP) 2010-01-12 US disclosed
US-7645830-B2 Polymer, crosslinked polymer, composition for solid polymer electrolyte, solid polymer electrolyte, and adhesive composition NIPPON SODA CO., LTD. (JP) 2010-01-12 US disclosed
US-20090118436-A1 Star Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-05-07 US disclosed
US-20090118436-A1 Star Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-05-07 US disclosed
WO-2009023762-A1 ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-19 WO disclosed
US-20080166636-A1 Polymer, Crosslinked Polymer, Composition for Solid Polymer Electrolyte, Solid Polymer Electrolyte, and Adhesive Composition NIPPON SODA CO., LTD. (JP) 2008-07-10 US disclosed
US-20080166636-A1 Polymer, Crosslinked Polymer, Composition for Solid Polymer Electrolyte, Solid Polymer Electrolyte, and Adhesive Composition NIPPON SODA CO., LTD. (JP) 2008-07-10 US disclosed
US-20070040145-A1 e.g.block copolymer of methoxypolyethylene glycol mono (meth)acrylate with monomers selected from unsaturated ether, alcohol, ester, nitrile, carboxy, anhydride etc.; excellent in thermal properties, physical properties and ion conductivity NIPPON SODA CO., LTD. (JP) 2007-02-22 US disclosed
US-20070040145-A1 e.g.block copolymer of methoxypolyethylene glycol mono (meth)acrylate with monomers selected from unsaturated ether, alcohol, ester, nitrile, carboxy, anhydride etc.; excellent in thermal properties, physical properties and ion conductivity NIPPON SODA CO., LTD. (JP) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120289731-A1 PHOTO-CROSSLINKABLE LIQUID CRYSTAL MONOMERS WITH OPTICAL ACTIVITY UACA, DLK1, DECR1 HSD17B10 42/4885THRB 4537/4885ALDH1A1 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.