Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23273490 | 0.92 | MEN1 (0.52) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL3668560 | 0.89 | SMN1; SMN2 (0.46) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL762575 | 0.89 | MAPT (0.52) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL7015793 | 0.88 | MAPT (0.48) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL3668042 | 0.88 | SMN1; SMN2 (0.45) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL27325815 | 0.86 | MAPT (0.47) | ALDH1A1L3MBTL1HTTMAPK1KMT2A | |
| SCHEMBL2087478 | 0.86 | KDM4E (0.54) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL14249239 | 0.83 | SMN1; SMN2 (0.49) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL738697 | 0.81 | MAPT (0.54) | ALDH1A1L3MBTL1HTTMAPK1KMT2A | |
| SCHEMBL29154915 | 0.80 | TDP1 (0.42) | ALDH1A1MAPK1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429969-A1 | NEW PIGMENT SYSTEM FOR COLORING CEMENT SYSTEMS, IN PARTICULAR CONCRETE | Harold Scholz&Co. GmbH (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20110071130-A1 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2011-03-24 | — | — | US | disclosed |
| US-20110071130-A1 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2011-03-24 | — | — | US | disclosed |
| US-20110071130-A1 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2011-03-24 | — | — | US | disclosed |
| WO-2010130314-A1 | NEW PIGMENT SYSTEM FOR COLORING CEMENT SYSTEMS, IN PARTICULAR CONCRETE | HAROLD SCHOLZ & CO. GMBH (DE) | 2010-11-18 | — | — | WO | disclosed |
| WO-2007133983-A2 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007133983-A2 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071130-A1 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | ADORA2A, ADORA2B, ADORA1 | ALDH1A1 521/4885L3MBTL1 4014/4885HTT 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.