Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 5/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP3 | P08254 | 5/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384292 | 0.91 | MMP3 (0.46) | ACEEPHX2MMP1MMP2MMP3 | |
| Homophenylalanine SCHEMBL7383933 | 0.85 | GGT1 (0.50) | ACEGGT1 | |
| Glutamic Acid SCHEMBL7375280 | 0.84 | GGT1 (0.49) | ACEGGT1 | |
| Cyclohexylglycyl SCHEMBL7423505 | 0.84 | ACE (0.46) | ACEEPHX2GGT1 | |
| SCHEMBL7383218 | 0.82 | GGT1 (0.53) | ACEGGT1 | |
| SCHEMBL6411223 | 0.82 | ACE (0.53) | ACE | |
| Serine SCHEMBL7384366 | 0.81 | GGT1 (0.48) | ACEGGT1 | |
| Phenylalanine SCHEMBL7432097 | 0.81 | ALPI (0.56) | ACEGGT1 | |
| SCHEMBL6423726 | 0.80 | GGT1 (0.57) | ACEGGT1 | |
| Leucine SCHEMBL6415294 | 0.80 | LTA4H (0.46) | MMP3GGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063991-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-1047450-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-0946166-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1999047138-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999032150-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |
| WO-1998026773-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR TREATING NEUROLOGICAL DISORDERS AND PROMOTING WOUND HEALING | WARNER-LAMBERT COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |