Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387785 | 0.80 | KMT2A (0.50) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7382672 | 0.79 | CHRM1 (0.42) | KMT2AMEN1HTR7ALDH1A1 | |
| SCHEMBL7391922 | 0.78 | ALDH1A1 (0.48) | KMT2AHTR7ALDH1A1 | |
| SCHEMBL7381582 | 0.78 | LMNA (0.53) | KMT2AHTR7ALDH1A1 | |
| SCHEMBL7387541 | 0.78 | LMNA (0.53) | KMT2AHTR7ALDH1A1 | |
| SCHEMBL7386994 | 0.76 | LMNA (0.54) | KMT2AHTR7ALDH1A1 | |
| SCHEMBL7393313 | 0.75 | DRD2 (0.58) | HTR7 | |
| SCHEMBL7388066 | 0.75 | ALDH1A1 (0.50) | KMT2AHTR7ALDH1A1 | |
| SCHEMBL7386508 | 0.74 | MAPT (0.61) | KMT2AHTR7ALDH1A1 | |
| SCHEMBL7390493 | 0.74 | MAPT (0.61) | KMT2AHTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |