Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385705 | 0.80 | KMT2A (0.53) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7277589 | 0.78 | KMT2A (0.52) | KMT2AMEN1OXER1ALDH1A1TSHR | |
| SCHEMBL14397448 | 0.77 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL17022682 | 0.76 | POLB (0.46) | OXER1ALDH1A1PLA2G2A | |
| SCHEMBL17022587 | 0.74 | OXER1 (0.62) | KMT2AMEN1OXER1ALDH1A1PLA2G2A | |
| SCHEMBL7381802 | 0.74 | LMNA (0.61) | KMT2AALDH1A1TSHR | |
| SCHEMBL7392527 | 0.74 | LMNA (0.61) | KMT2AALDH1A1TSHR | |
| SCHEMBL7278316 | 0.73 | EGFR (0.65) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL984736 | 0.73 | EGFR (0.65) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL30443220 | 0.73 | EGFR (0.65) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |