Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3168948 | 0.75 | NISCH (0.73) | NISCHMAOAMAOBADRA1AADRA1D | |
| SCHEMBL10719216 | 0.75 | NQO1 (0.52) | — | |
| SCHEMBL2716599 | 0.72 | LMNA (0.68) | MAOB | |
| SCHEMBL8469779 | 0.72 | ADRA1A (0.47) | NISCHMAOAMAOBADRA1AADRA1D | |
| SCHEMBL271585 | 0.72 | MMP8 (0.59) | MAOA | |
| SCHEMBL6710817 | 0.71 | NISCH (0.71) | NISCHMAOAMAOBADRA1AADRA1D | |
| SCHEMBL28462964 | 0.71 | SMN1; SMN2 (0.64) | — | |
| SCHEMBL546875 | 0.71 | NISCH (1.00) | NISCHMAOAMAOBADRA1AADRA1D | |
| Hydrochloric Acid SCHEMBL11251146 | 0.70 | NISCH (0.69) | NISCHMAOAMAOBADRA1AADRA1D | |
| SCHEMBL11255453 | 0.70 | NISCH (0.69) | NISCHMAOAMAOBADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620991-A | ANTICOAGULANTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |