Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389627 | 0.83 | CYP19A1 (0.42) | GAAALDH1A1MAPT | |
| SCHEMBL7385948 | 0.82 | CYP19A1 (0.41) | KMT2AGAARAB9ATP53 | |
| SCHEMBL7379476 | 0.80 | CYP19A1 (0.40) | — | |
| SCHEMBL7378709 | 0.80 | PTGS2 (0.47) | — | |
| SCHEMBL9838641 | 0.79 | PTPN2 (0.53) | KMT2AALDH1A1MAPT | |
| SCHEMBL4035788 | 0.76 | HTR2A (0.47) | ALDH1A1MAPTRAB9A | |
| SCHEMBL10379523 | 0.74 | CYP19A1 (0.63) | KMT2AGAAALDH1A1MAPTSLC6A3 | |
| SCHEMBL10608166 | 0.72 | CYP17A1 (0.56) | KMT2AGAAALDH1A1MAPTSLC6A3 | |
| SCHEMBL427393 | 0.72 | KMT2A (0.56) | KMT2AGAAMAPTSLC6A3RAB9A | |
| SCHEMBL1345244 | 0.72 | KMT2A (0.56) | KMT2AGAAMAPTSLC6A3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | claimed |
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | disclosed |