Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MME | P08473 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381804 | 0.89 | ITGB3 (0.67) | ITGB3ITGA2BMMEMMEL1PLA2G2A | |
| SCHEMBL7353849 | 0.88 | ITGB3 (0.46) | ITGB3ITGA2BALDH1A1KMT2AHDAC3 | |
| SCHEMBL7323685 | 0.87 | LMNA (0.47) | ITGB3ITGA2BALDH1A1KMT2A | |
| SCHEMBL7389607 | 0.85 | ITGB3 (0.50) | ITGB3ITGA2BALDH1A1MMEMMEL1 | |
| SCHEMBL7378676 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1KMT2APLA2G2A | |
| SCHEMBL7386244 | 0.82 | ITGB3 (0.79) | ITGB3ITGA2BALDH1A1MMEKMT2A | |
| SCHEMBL7388729 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1KMT2AHDAC3 | |
| SCHEMBL7385504 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1KMT2A | |
| SCHEMBL7384462 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BALDH1A1KMT2AHDAC3 | |
| SCHEMBL7388815 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BALDH1A1KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220050-A | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-06-15 | — | — | US | claimed |
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | claimed |
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0513810-A1 | Peptide mimetic compounds useful as platelet aggregation inhibitors | G.D. Searle & Co. (US) | 1992-11-19 | — | — | EP | disclosed |