Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320119 | 0.91 | RAB9A (0.43) | LMNAITGB3ITGA2BALDH1A1KMT2A | |
| SCHEMBL7353849 | 0.88 | ITGB3 (0.46) | ITGB3ITGA2BALDH1A1KMT2ACA12 | |
| SCHEMBL7386249 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BALDH1A1KMT2A | |
| SCHEMBL7318568 | 0.85 | ITGB3 (0.58) | LMNAITGB3ITGA2BALDH1A1KMT2A | |
| SCHEMBL7389607 | 0.80 | ITGB3 (0.50) | ITGB3ITGA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL7351149 | 0.78 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1KMT2AKDM4E | |
| SCHEMBL7378676 | 0.78 | ITGB3 (0.49) | LMNAITGB3ITGA2BALDH1A1KMT2A | |
| SCHEMBL7357417 | 0.77 | ITGB3 (0.46) | ITGB3ITGA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL7388729 | 0.77 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1KMT2A | |
| SCHEMBL7348963 | 0.77 | ITGB3 (0.50) | ITGB3ITGA2BSMN1; SMN2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | claimed |
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | disclosed |