Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059553 | 1.00 | TDP1 (0.75) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL10792885 | 1.00 | TDP1 (0.75) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL101 | 0.87 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Benzene SCHEMBL6890099 | 0.87 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL5028587 | 0.87 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL2085135 | 0.87 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL1654102 | 0.84 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL21296017 | 0.84 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL4053762 | 0.84 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL5839090 | 0.84 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968406-A | Polycyclic olefin polymers containing acrylate functionality and acrylate/maleimide crosslinkers as B-stageable compositions in low loss applications | 普罗米鲁斯有限责任公司 | 2025-05-09 | — | — | CN | claimed |
| CN-118956043-B | Light power cable for ship and processing method thereof | 广州澳兴光电传输科技股份有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-118956043-A | Light power cable for ship and processing method thereof | 广州澳兴光电传输科技股份有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-116368165-A | Polycyclic olefin composition for low loss films with improved thermal properties | 普罗米鲁斯有限责任公司 | 2023-06-30 | — | — | CN | claimed |
| CN-110330528-A | A kind of preparation method of bis- (triphenylphosphine) palladium bromides | 西安凯立新材料股份有限公司 | 2019-10-15 | — | — | CN | claimed |
| WO-2005066109-A1 | A PROCESS FOR THE PREPARATION OF 2-HYDROXY CARBOXYLIC ACIDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-21 | — | — | WO | claimed |
| US-20050143600-A1 | Process for the preparation of 2-hydroxy carboxylic acids | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-06-30 | — | — | US | claimed |
| EP-1169295-B1 | PREPARATION OF SUBSTITUTED AROMATIC CARBOXYLIC ACID ESTERS | EASTMAN CHEM CO (US) | 2004-07-28 | — | — | EP | claimed |
| US-20020040159-A1 | Preparation of substituted aromatic carboxylic acid esters | EASTMAN CHEMICAL COMPANY | 2002-04-04 | — | — | US | claimed |
| EP-1169295-A1 | PREPARATION OF SUBSTITUTED AROMATIC CARBOXYLIC ACID ESTERS | EASTMAN CHEMICAL COMPANY (US) | 2002-01-09 | — | — | EP | claimed |
| US-6337418-B1 | PALLADIUM COMPLEX-CATALYZED CARBOXYLATION OF NITRO NITRO-SUBSTITUTED ARYL HALIDE, IN ABSENCE OF WATER AND OXYGEN, WITH CARBON MONOXIDE, AN ALCOHOL, PROTON ACCEPTOR; OPTIONAL SULFIDING WITH THIOLATE ANION | EASTMAN CHEMICAL CO. | 2002-01-08 | — | — | US | claimed |
| WO-2000061538-A1 | PREPARATION OF SUBSTITUTED AROMATIC CARBOXYLIC ACID ESTERS | EASTMAN CHEMICAL COMPANY (US) | 2000-10-19 | — | — | WO | claimed |
| US-4820823-A | ONE STEP CARBONYLATION OF ORGANIC HALIDE WITH CARBON MONOXIDE AND WATER USING BASE AND PALLADIUM CATALYST | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1989-04-11 | — | — | US | claimed |
| JP-61027937-A | — | — | None | — | — | JP | disclosed |
| US-12559446-B2 | Hydrogenation of l-sorbose | BASF SE (DE) | 2026-02-24 | — | — | US | disclosed |
| EP-3921298-B1 | PROCESS FOR THE PRODUCTION OF ACETALS FROM CARBON DIOXIDE | BASF SE (DE) | 2025-12-03 | — | — | EP | disclosed |
| EP-0077542-A1 | Process for preparing diesters of malonic acid | UBE INDUSTRIES, LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| EP-0045520-A1 | Pyrimido-(4,5-d)(2)-benzazepines, process for their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-02-10 | — | — | EP | disclosed |
| US-4128554-A | Process for the preparation of carboxylic acid amides from organic halides | UNIVERSITY OF DELAWARE (US) | 1978-12-05 | — | — | US | disclosed |
| US-3988358-A | Process for the preparation of carboxylic acid esters from organic halides | THE UNIVERSITY OF DELAWARE (US) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040159-A1 | Preparation of substituted aromatic carboxylic acid esters | TH, DDC, PAH | TDP1 1898/4885CYP3A4 32/4885ESR1 822/4885 |
| US-12559446-B2 | Hydrogenation of l-sorbose | ME1, LDHA, L1CAM | TDP1 3624/4885CYP3A4 1388/4885ESR1 2347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.