Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL738502 | 0.89 | NPC1 (0.43) | AKT1CNR1TRPV1HPGDPOLB | |
| SCHEMBL740150 | 0.88 | HSD11B1 (0.39) | AKT1HDAC1 | |
| SCHEMBL738378 | 0.87 | CNR1 (0.41) | CNR1TRPV1HPGD | |
| SCHEMBL738736 | 0.86 | MLYCD (0.43) | CNR1TRPV1MEN1MAPTKMT2A | |
| SCHEMBL738595 | 0.86 | MLYCD (0.44) | CNR1MEN1MAPTKMT2A | |
| SCHEMBL739725 | 0.85 | RPA1 (0.45) | AKT1EPHX2KMT2AHDAC1 | |
| SCHEMBL738000 | 0.85 | ULK1 (0.36) | EPHX2NR1H4MEN1KMT2AGCGR | |
| SCHEMBL738675 | 0.85 | HDAC4 (0.41) | AKT1MEN1CYP2C19KMT2ANPSR1 | |
| SCHEMBL738957 | 0.85 | HDAC1 (0.44) | EPHX2MAPTHDAC1 | |
| SCHEMBL738500 | 0.84 | HDAC4 (0.46) | TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL CORPORATION (JP) | 2020-12-29 | — | — | US | disclosed |
| US-20200155511-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2020-05-21 | — | — | US | disclosed |
| US-10596157-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL CORPORATION (JP) | 2020-03-24 | — | — | US | disclosed |
| US-20180318266-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-11-08 | — | — | US | disclosed |
| US-20170065565-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| EP-1731512-B9 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | NISSAN CHEMICAL IND LTD (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-20150105398-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2015-04-16 | — | — | US | disclosed |
| US-8946492-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| EP-1731512-B1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | NISSAN CHEMICAL IND LTD (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-20130296559-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2013-11-07 | — | — | US | disclosed |
| US-8492311-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20120172615-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| US-8138213-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20110251398-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-10-13 | — | — | US | disclosed |
| US-8022089-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-7662972-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-22 | — | — | US | disclosed |
| EP-1731512-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105398-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | AKT1 2524/4885KCNH2 100/4885CACNA1I 1959/4885 |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | HDAC7, ACHE, BRDT | AKT1 2413/4885KCNH2 53/4885CACNA1I 318/4885 |
| US-10596157-B2 | Isoxazoline-substituted benzamide compound and pesticide | CHRM3, C3AR1, C9 | AKT1 2488/4885KCNH2 86/4885CACNA1I 1572/4885 |
| US-20120172615-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | AKT1 1853/4885KCNH2 103/4885CACNA1I 1966/4885 |
| US-20180318266-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | CHRM3, C3AR1, C9 | AKT1 2488/4885KCNH2 86/4885CACNA1I 1572/4885 |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | ATM, CHRM1, NAT1 | AKT1 2369/4885KCNH2 132/4885CACNA1I 2269/4885 |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | C3AR1, C5, C9 | AKT1 2347/4885KCNH2 167/4885CACNA1I 2129/4885 |
| US-20130296559-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C5, C3AR1, C9 | AKT1 2392/4885KCNH2 163/4885CACNA1I 2115/4885 |
| US-20110251398-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | CBR3, CHRM1, CBR1 | AKT1 992/4885KCNH2 157/4885CACNA1I 1666/4885 |
| US-20170065565-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | AKT1 2449/4885KCNH2 134/4885CACNA1I 1802/4885 |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | CHRM1, DDT, ATM | AKT1 3228/4885KCNH2 928/4885CACNA1I 2681/4885 |
| US-20200155511-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | AKT1 2347/4885KCNH2 167/4885CACNA1I 2129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.