Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREB1 | P16220 | 6/20 | 0.72 |
| ▸ | FLT3 | P36888 | 3/20 | 0.72 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.72 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.72 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.72 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.72 |
| ▸ | PTPRS | Q13332 | 2/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | GABRP | O00591 | 3/20 | 0.66 |
| ▸ | GABRD | O14764 | 3/20 | 0.66 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.66 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.66 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.66 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.66 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.66 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.66 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966701 | 0.90 | ABCB1 (0.66) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL739689 | 0.89 | CREB1 (0.60) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL738096 | 0.88 | CREB1 (0.69) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Oroxylin A SCHEMBL30452350 | 0.84 | CREB1 (1.00) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Oroxylin A SCHEMBL431423 | 0.84 | CREB1 (1.00) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Baicalein SCHEMBL28132467 | 0.83 | ABCB1 (0.89) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL971997 | 0.82 | CREB1 (0.75) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL27712859 | 0.82 | TYR (0.76) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Baicalein SCHEMBL28910096 | 0.82 | ABCB1 (0.86) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL972514 | 0.81 | CREB1 (1.00) | CREB1FLT3PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138165-B2 | Chromones and chromone derivatives and uses thereof | JENKEN BIOSCIENCES, INC. (US) | 2012-03-20 | — | — | US | claimed |
| EP-1556031-A4 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | JENKEN BIOSCIENCES INC (US) | 2009-03-25 | — | — | EP | claimed |
| US-20060142211-A1 | Chromones and chromone derivatives and uses thereof | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2006-06-29 | — | — | US | claimed |
| EP-1556031-A2 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | Jenken Bioscience, Inc. (US) | 2005-07-27 | — | — | EP | claimed |
| WO-2004037193-A2 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | JENKEN BIOSCIENCES, INC. (US) | 2004-05-06 | — | — | WO | claimed |
| US-8138165-B2 | Chromones and chromone derivatives and uses thereof | JENKEN BIOSCIENCES, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| EP-1556031-A4 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | JENKEN BIOSCIENCES INC (US) | 2009-03-25 | — | — | EP | disclosed |
| US-20060142211-A1 | Chromones and chromone derivatives and uses thereof | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2006-06-29 | — | — | US | disclosed |
| EP-1556031-A2 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | Jenken Bioscience, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037193-A2 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | JENKEN BIOSCIENCES, INC. (US) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142211-A1 | Chromones and chromone derivatives and uses thereof | PROC, HMGB1, PYCARD | CREB1 2646/4885FLT3 2228/4885PRSS1 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.