Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | UGCG | Q16739 | 1/20 | 0.47 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388987 | 0.85 | LTA4H (0.56) | HRH3SIGMAR1GBA1UGCGGBA2 | |
| SCHEMBL7389601 | 0.85 | LTA4H (0.56) | HRH3SIGMAR1GBA1UGCGGBA2 | |
| SCHEMBL7387110 | 0.84 | LTA4H (0.57) | HRH3SIGMAR1GBA1UGCGGBA2 | |
| SCHEMBL7384082 | 0.81 | HRH3 (0.75) | HRH3 | |
| SCHEMBL7395255 | 0.79 | TEAD3 (0.59) | HRH3HRH1TMEM97SIGMAR1 | |
| SCHEMBL7389094 | 0.79 | HRH3 (0.72) | HRH3SIGMAR1 | |
| SCHEMBL7391532 | 0.79 | GBA1 (0.54) | HRH3SLC6A2SLC6A4SIGMAR1GBA1 | |
| SCHEMBL7387064 | 0.78 | KDM4E (0.49) | TMEM97SIGMAR1 | |
| SCHEMBL31163852 | 0.77 | UGCG (0.68) | GBA1UGCGGBA2 | |
| SCHEMBL7389893 | 0.77 | ALDH1A1 (0.48) | HRH3KCNH2GBA1UGCGGBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |