Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 5/20 | 1.00 |
| ▸ | DRD1 | P21728 | 5/20 | 1.00 |
| ▸ | DRD2 | P14416 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | CHRNB2 | P17787 | 2/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 2/20 | 1.00 |
| ▸ | CHRNA4 | P43681 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 1.00 |
| ▸ | CSNK2B | P67870 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boldine SCHEMBL13459203 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| Boldine SCHEMBL29973042 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| Boldine SCHEMBL177549 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| Boldine SCHEMBL177550 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| Boldine SCHEMBL30184400 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| Boldine SCHEMBL3060583 | 0.99 | ALDH1A1 (0.98) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| Predicentrine SCHEMBL25844649 | 0.95 | ALDH1A1 (0.91) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| Predicentrine SCHEMBL4410538 | 0.95 | ALDH1A1 (0.91) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| Boldine SCHEMBL420488 | 0.94 | ALDH1A1 (0.89) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| SCHEMBL4854015 | 0.94 | HTR7 (1.00) | ALDH1A1HSD17B10HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594033-A | Secoaporphine compound on arrhythmia | NATIONAL SCIENCE COUNCIL (TW) | 1997-01-14 | — | — | US | disclosed |