Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396722 | 0.87 | S1PR1 (0.52) | S1PR1HDAC1ITGB3ITGA2BMEN1 | |
| SCHEMBL4537533 | 0.81 | MEN1 (0.55) | MEN1KMT2AFFAR1FFAR4SMN1; SMN2 | |
| SCHEMBL7390478 | 0.80 | CYP4F2 (0.52) | S1PR1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL7275491 | 0.75 | S1PR1 (0.52) | S1PR1HDAC1ITGB3ITGA2BMEN1 | |
| SCHEMBL1675924 | 0.75 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL7275097 | 0.75 | S1PR1 (0.52) | S1PR1HDAC1ITGB3ITGA2BMEN1 | |
| SCHEMBL8415373 | 0.75 | ITGB3 (0.41) | S1PR1ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL7390958 | 0.75 | RAB9A (0.42) | S1PR1HDAC1MEN1KMT2ARAB9A | |
| SCHEMBL7274080 | 0.74 | ITGB3 (0.74) | S1PR1ITGB3ITGA2B | |
| SCHEMBL7845059 | 0.72 | MEN1 (0.53) | HDAC1MEN1KMT2AFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |