Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384580 | 0.87 | ALDH1A1 (0.46) | CAPN1ALDH1A1CNR1KMT2AITGB3 | |
| SCHEMBL7385254 | 0.86 | ALDH1A1 (0.45) | CAPN1ALDH1A1GAAKMT2A | |
| SCHEMBL7386548 | 0.84 | ITGB3 (0.46) | ALDH1A1GAAKMT2AITGB3ITGA2B | |
| SCHEMBL7386056 | 0.82 | CTSG (0.52) | CAPN1ALDH1A1 | |
| SCHEMBL7386158 | 0.82 | ALDH1A1 (0.45) | CAPN1ALDH1A1ITGB3ITGA2BPOLB | |
| SCHEMBL7385771 | 0.81 | HDAC1 (0.54) | KMT2A | |
| SCHEMBL7382682 | 0.81 | KMT2A (0.41) | ALDH1A1KMT2APOLB | |
| SCHEMBL7390554 | 0.81 | CTSG (0.43) | ALDH1A1KMT2A | |
| SCHEMBL7388722 | 0.81 | HDAC1 (0.54) | ALDH1A1 | |
| SCHEMBL7380004 | 0.81 | HDAC1 (0.41) | KMT2AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220050-A | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-06-15 | — | — | US | claimed |
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | claimed |
| US-5220050-A | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-06-15 | — | — | US | disclosed |
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0513810-A1 | Peptide mimetic compounds useful as platelet aggregation inhibitors | G.D. Searle & Co. (US) | 1992-11-19 | — | — | EP | disclosed |