Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 8/20 | 0.38 |
| ▸ | USP7 | Q93009 | 2/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | BAX | Q07812 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478847 | 0.79 | LTA4H (0.34) | GSTP1LTA4HTSHRNCOA1NCOA3 | |
| SCHEMBL22129263 | 0.76 | PTGS1 (0.35) | USP7GCGRLMNAHTT | |
| SCHEMBL8476457 | 0.75 | HTT (0.33) | GSTP1LTA4HHTT | |
| SCHEMBL8476959 | 0.73 | PDCD1 (0.36) | USP7GCGRLMNA | |
| SCHEMBL8477540 | 0.73 | PDE4B (0.42) | USP7GCGRTSHR | |
| SCHEMBL8474107 | 0.71 | LTA4H (0.34) | GSTP1LTA4H | |
| SCHEMBL8478249 | 0.69 | LTA4H (0.41) | GSTP1LTA4H | |
| SCHEMBL8479699 | 0.69 | HEXA (0.38) | — | |
| SCHEMBL8479756 | 0.69 | HEXA (0.38) | — | |
| SCHEMBL9730506 | 0.67 | GSTP1 (0.57) | GSTP1LTA4HTSHRNCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252178-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-10-30 | — | — | EP | claimed |
| WO-2001040262-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-06-07 | — | — | WO | claimed |