Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.42 |
| ▸ | PDE4A | P27815 | 5/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.42 |
| ▸ | MGAM | O43451 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | SI | P14410 | 4/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476328 | 0.88 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL8479699 | 0.86 | HEXA (0.38) | MGAMGAASIMGAM2PTGS2 | |
| SCHEMBL8479825 | 0.86 | USP7 (0.33) | MGAMGAASIMGAM2USP7 | |
| SCHEMBL8477677 | 0.85 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL22129263 | 0.82 | PTGS1 (0.35) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL8479313 | 0.79 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4DMGAM | |
| SCHEMBL8476959 | 0.79 | PDCD1 (0.36) | GAAMAPTNPC1RAB9APTGS1 | |
| SCHEMBL8478847 | 0.76 | LTA4H (0.34) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL8475248 | 0.75 | MGAM (0.33) | MGAMGAASIMGAM2GCGR | |
| SCHEMBL8481674 | 0.75 | PTGS2 (0.37) | PDE4BPDE4APDE4CPDE4DMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |