SCHEMBL22129263

SCHEMBL22129263

CCc1[c]cc(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
GCGR P47871 2/20 0.34
DHFR P00374 1/20 0.34
HEXA P06865 1/20 0.34
HEXB P07686 1/20 0.34
USP7 Q93009 2/20 0.34
TP53 P04637 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
DPP4 P27487 1/20 0.31
ADORA3 P0DMS8 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8476959 0.86 PDCD1 (0.36) PTGS1PTGS2GCGRDHFRHEXA
SCHEMBL8477540 0.82 PDE4B (0.42) PTGS1PTGS2GCGRUSP7MAPT
SCHEMBL8478847 0.79 LTA4H (0.34) PTGS2L3MBTL1ESR1ESR2MAPT
SCHEMBL8477966 0.78 DHFR (0.38) PTGS1PTGS2GCGRDHFRHEXA
SCHEMBL8474999 0.77 GAA (0.41) USP7L3MBTL1LMNAMAPT
SCHEMBL8474110 0.76 GCGR (0.35) GCGRDHFRMAPTPDCD1CD274
SCHEMBL7387752 0.76 GSTP1 (0.40) GCGRUSP7LMNAHTT
SCHEMBL12816030 0.75 CYP2A6 (0.36) PTGS1PTGS2ESR2LMNAMAPT
SCHEMBL8476328 0.73 PDE4B (0.40) GCGRADORA3ADORA2AADORA1NPC1
SCHEMBL8477304 0.73 PDCD1 (0.38) PTGS1GCGRESR2PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020124645-A1 STABLE DISPERSANT AND APPLICATION THEREOF IN PREPARING COPOLYMER POLYOLS 万华化学集团股份有限公司 2020-06-25 WO claimed