Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72819 | 0.91 | MAOB (0.45) | MAOBMAPTNPC1RAB9ACA12 | |
| SCHEMBL72182 | 0.85 | MAOB (0.53) | MAOBMAPTNPC1RAB9ACA12 | |
| SCHEMBL91556 | 0.81 | MAOB (0.57) | MAOBMAPTNPC1RAB9ACA12 | |
| SCHEMBL71626 | 0.80 | PKM (0.57) | MAOBMAPTNPC1SMN1; SMN2 | |
| SCHEMBL5708317 | 0.80 | SMN1; SMN2 (0.43) | MAOBMAPTNPC1RAB9AGAA | |
| SCHEMBL3579447 | 0.79 | ITGB1 (0.56) | MAOBMAPTNPC1RAB9A | |
| SCHEMBL70950 | 0.76 | MAOB (0.50) | MAOBMAPTNPC1RAB9ACA12 | |
| SCHEMBL91543 | 0.76 | RAB9A (0.64) | MAOBMAPTNPC1RAB9ACA12 | |
| SCHEMBL23218036 | 0.76 | MAPT (0.47) | MAOBMAPTGAASMN1; SMN2 | |
| SCHEMBL91531 | 0.76 | MAOB (0.54) | MAOBMAPTNPC1RAB9ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961750-B1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO CO LTD (JP) | 2013-09-18 | — | — | EP | disclosed |