Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753583 | 0.71 | ALDH1A1 (0.47) | KMT2AMAPTTSHRCYP1A2CYP2C9 | |
| SCHEMBL2654623 | 0.67 | TSHR (0.40) | KMT2ATSHRCYP1A2CYP2C9GPR119 | |
| SCHEMBL20424119 | 0.66 | CYP1A2 (0.37) | KMT2AMAPTHSD17B10TSHRCYP1A2 | |
| SCHEMBL29530296 | 0.66 | CYP1A2 (0.37) | KMT2AMAPTHSD17B10TSHRCYP1A2 | |
| SCHEMBL23850127 | 0.66 | GRIN2B (0.55) | KMT2AGRIN2BCYP3A4MAPTTSHR | |
| SCHEMBL25520144 | 0.65 | HRH3 (0.56) | HSD17B10HPGDGPR119MEN1HRH3 | |
| SCHEMBL12207096 | 0.64 | TPSAB1 (0.39) | CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL12233178 | 0.64 | HTT (0.36) | KMT2AMAPTHSD17B10TSHRCYP1A2 | |
| SCHEMBL14752995 | 0.64 | HTT (0.36) | KMT2AMAPTHSD17B10TSHRCYP1A2 | |
| SCHEMBL16965092 | 0.64 | ALDH1A1 (0.42) | KMT2AMAPTTSHRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023265-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999018073-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1999-04-15 | — | — | WO | disclosed |