Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427630 | 0.78 | LMNA (0.42) | ALDH1A1MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL28617660 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTSMN1; SMN2POLB | |
| SCHEMBL465266 | 0.76 | LMNA (0.41) | ALDH1A1SMN1; SMN2POLBLMNAGAA | |
| SCHEMBL10767133 | 0.75 | TSHR (0.52) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8896301 | 0.73 | L3MBTL1 (0.42) | ALDH1A1MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL9422948 | 0.73 | POLB (0.45) | ALDH1A1MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL4301644 | 0.73 | LMNA (0.58) | ALDH1A1HPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2392777 | 0.72 | ELANE (0.41) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL42561 | 0.72 | LMNA (0.38) | ALDH1A1SMN1; SMN2POLBLMNAGAA | |
| SCHEMBL7388012 | 0.71 | KMT2A (0.39) | ALDH1A1HPGDMAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |