Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388273 | 1.00 | HPGD (0.43) | HPGDNPSR1HSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL7322469 | 0.84 | HPGD (0.46) | HPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL7320276 | 0.82 | HPGD (0.45) | HPGDKMT2ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL7321829 | 0.75 | ALDH1A1 (0.47) | HPGDHSD17B10KMT2AALDH1A1MEN1 | |
| SCHEMBL7290887 | 0.72 | PKM (0.57) | HPGDALDH1A1PKM | |
| SCHEMBL10516627 | 0.71 | PREP (0.49) | NPSR1HSD17B10 | |
| SCHEMBL10516636 | 0.71 | PREP (0.49) | NPSR1HSD17B10 | |
| SCHEMBL7317320 | 0.71 | KMT2A (0.45) | HPGDKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7319764 | 0.70 | GAA (0.47) | HPGDKMT2ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL7265568 | 0.70 | HPGD (0.52) | HPGDKMT2AALDH1A1PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461677-B1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |
| EP-0461677-A1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |