Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320276 | 0.88 | HPGD (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10585933 | 0.88 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1HPGDDPP4DPP8 | |
| SCHEMBL7317320 | 0.88 | KMT2A (0.45) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7320636 | 0.87 | TPSAB1 (0.40) | — | |
| SCHEMBL7321829 | 0.85 | ALDH1A1 (0.47) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7319189 | 0.85 | HDAC3 (0.46) | LMNAHTR1AHTR7NPC1RAB9A | |
| SCHEMBL7316783 | 0.85 | P2RX7 (0.43) | GAAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7366403 | 0.80 | NPC1 (0.48) | MEN1KMT2ASMN1; SMN2TSHRNPC1 | |
| SCHEMBL8637779 | 0.80 | PREP (0.53) | GAAKMT2AALDH1A1HTTLMNA | |
| SCHEMBL7266943 | 0.80 | DPP4 (0.56) | GAAMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |