Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395998 | 0.87 | ELANE (0.43) | KDM4EHDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7402117 | 0.82 | KDM4E (0.61) | KDM4EHDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7395145 | 0.81 | GUSB (0.47) | KDM4EALDH1A1 | |
| SCHEMBL7398683 | 0.81 | ALDH1A1 (0.49) | KDM4EHDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7396027 | 0.78 | HPSE (0.49) | KDM4EHDAC6MEN1KMT2AALDH1A1 | |
| SCHEMBL7393381 | 0.77 | PDE5A (0.50) | KDM4EAURKAALDH1A1 | |
| SCHEMBL7388752 | 0.76 | KDM4E (0.46) | KDM4EHDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL4939590 | 0.76 | ALOX15 (0.51) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL259502 | 0.74 | ALDH1A1 (0.50) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7396372 | 0.73 | RAB9A (0.53) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | claimed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | claimed |
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |