Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386703 | 0.87 | CHEK2 (0.48) | KDM4ECHEK2AMY1AALDH1A1KMT2A | |
| SCHEMBL7402117 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL7396027 | 0.84 | HPSE (0.49) | KDM4ECHEK2AMY1AALDH1A1KMT2A | |
| SCHEMBL7396372 | 0.83 | RAB9A (0.53) | CHEK2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL23758270 | 0.81 | AURKA (0.55) | KDM4EAMY1AALDH1A1KMT2AHPGD | |
| SCHEMBL7388111 | 0.81 | AMY1A (0.66) | KDM4ECHEK2AMY1AALDH1A1KMT2A | |
| SCHEMBL7398683 | 0.80 | ALDH1A1 (0.49) | KDM4ECHEK2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7392370 | 0.79 | AMY1A (0.46) | KDM4EAMY1AALDH1A1RAB9ANPC1 | |
| SCHEMBL7388362 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3336441 | 0.76 | KDM4E (0.59) | KDM4EALDH1A1KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | claimed |
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |