Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239389 | 0.92 | MEN1 (0.46) | TDP1L3MBTL1MEN1KMT2AHRH3 | |
| SCHEMBL6895507 | 0.87 | LTA4H (0.55) | TDP1L3MBTL1 | |
| SCHEMBL3886046 | 0.84 | CA1 (0.44) | TDP1MEN1KMT2AHRH3IDO1 | |
| SCHEMBL31018369 | 0.83 | L3MBTL1 (0.51) | TDP1L3MBTL1HRH3NAAAKCNA3 | |
| SCHEMBL10826161 | 0.82 | L3MBTL1 (0.54) | TDP1L3MBTL1HRH3NAAAKCNA3 | |
| SCHEMBL6941525 | 0.82 | L3MBTL1 (0.54) | TDP1L3MBTL1HRH3NAAAKCNA3 | |
| SCHEMBL10825883 | 0.82 | L3MBTL1 (0.54) | TDP1L3MBTL1HRH3NAAAKCNA3 | |
| SCHEMBL3289641 | 0.82 | L3MBTL1 (0.54) | TDP1L3MBTL1HRH3NAAAKCNA3 | |
| SCHEMBL31018373 | 0.81 | L3MBTL1 (0.50) | TDP1L3MBTL1HRH3NAAAKCNA3 | |
| SCHEMBL7449325 | 0.81 | TDP1 (0.61) | TDP1L3MBTL1MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |