SCHEMBL73893

SCHEMBL73893

C=C(C)C(=O)OCOC1Cc2ccccc2C1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
IDO1 P14902 2/20 0.37
MTNR1A P48039 4/20 0.37
MTNR1B P49286 4/20 0.37
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
TSHR P16473 1/20 0.35
ELANE P08246 1/20 0.35
FABP7 O15540 1/20 0.35
FABP5 Q01469 1/20 0.35
FFAR1 O14842 1/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
THRB P10828 1/20 0.33
NR1D1 P20393 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92269 0.92 ALDH1A1 (0.35) ALDH1A1IDO1MTNR1AMTNR1BCA1
SCHEMBL92272 0.90 MTNR1A (0.43) ALDH1A1MTNR1AMTNR1BPRMT5WDR77
SCHEMBL92273 0.89 CA1 (0.36) ALDH1A1IDO1MTNR1AMTNR1BCA1
SCHEMBL9891413 0.79 FABP7 (0.45) ALDH1A1IDO1MTNR1AMTNR1BELANE
SCHEMBL5528985 0.77 ALDH1A1 (0.47) ALDH1A1CA1CA2TSHRPOLB
SCHEMBL92301 0.76 IDO1 (0.44) ALDH1A1IDO1FFAR1
SCHEMBL92238 0.75 IDO1 (0.36) IDO1MTNR1AMTNR1BELANEFABP7
SCHEMBL92271 0.74 FFAR1 (0.37) IDO1MTNR1AMTNR1BELANEFABP7
SCHEMBL92270 0.74 IDO1 (0.47) ALDH1A1IDO1FFAR1HTT
SCHEMBL16660502 0.74 ELANE (0.47) MTNR1AMTNR1BELANEFFAR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129086-B2 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-8129086-B2 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-8129086-B2 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same PRRC2A, PUF60, POLR2B ALDH1A1 3867/4885IDO1 4883/4885MTNR1A 4126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.